CXCR3 antibody (PE-Cy7)

Catalog No. ABIN7674018

The Mouse Monoclonal anti-CXCR3 antibody has been validated for FACS. It is suitable to detect CXCR3 in samples from Human.

Quick Overview for CXCR3 antibody (PE-Cy7) (ABIN7674018)

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCR3 antibody is conjugated to PE-Cy7

Application: Flow Cytometry (FACS)

Clone: G025H7

Product Details anti-CXCR3 Antibody (PE-Cy7)

Purpose: PE-Cy7 Anti-Human CD183/CXCR3 Antibody

Purification: 0

Purity: 0

Isotype: IgG1, kappa

Application Details

Application Notes: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: 4 °C

Storage Comment: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: CD183

Background:

Synonyms: CKR-L2|CXC-R3|CXCR-3|CXCR3|GPR9

Background: Human CXCR3, also known as GPR9, is a chemokine receptor that binds CXCL9, CXCL10, and CXCL11. It is a 38 kD seven-pass transmembrane receptor coupled to G-protein. CXCR3 is highly expressed by T cells (Th1), natural killer cells (NK cells), dendritic cells, mast cells, alveolar macrophages, eosinophils, and human airway epithelial cells. CXCR3 is important for effector lymphocyte recruitment into inflamed tissue in various inflammatory and autoimmune diseases, such as chronically inflamed liver, Crohn's disease, rheumatoid arthritis, multiple sclerosis, and inflammatory skin diseases.

Molecular Weight: 0

Gene ID: 2833

UniProt: P49682